How to break the cycle

…I don’t have a darn clue. 
  I’ve been struggling with the same issue for years now.  Because of the nature of the physical work of shoveling shit for 35 years… and the nature of bending over a computer keyboard on and off for various work related stuff over the years…   I’ve got arthritis in my neck and muscles spasms in the neck/shoulder area that occasionally FLARE. 
     Now throw in High Blood Pressure.  And medicine sensitivities galore. 
  Here’s why that’s aggravating as hell –  I hate BP meds, they make me feel like a slug and aren’t really effective.  I’ve tried three so far – bleh.   If I lose 10-15 lbs, which is about what I’ve gained over the years that I shouldn’t have… the numbers might come down some.  So I start doing some intensive treadmill walking/hiking and a few Yoga routines.  Which throws my neck and shoulders into a tizzy.  Which causes pain, which spikes the blood pressure. 
   Now throw in Anxiety… because when I feel like crap, that factors in too.  The muscle relaxants that are prescribed when the pain gets real bad make me feel like a zombie. Anti inflammatories make me stomach sick.  The Anxiety spirals, the muscles spasm more… 
 and still there is shit to shovel and documents to edit. 
  I’m not getting rid of the horses/chickens/rabbits.   I’m not quitting my day job.  I really need to keep up exercise regimen for health and well being.  
 So I ice my neck. I go to Physical Therapy.  I try to eat almost nothing to lose that 10-15 lbs, and it gets somewhere and then I fall back.  
Round and round it goes, when she’ll figure out what works for good, no one knows.   Or maybe I just don’t want to accept it.  
Anyway… have you found yourself in a negative life cycle that you’d love to resolve?  Did you manage to do so?  What worked for you, do tell…